Role of heavy metals composition in cardiac vascular diseased patients

This study was focused to quantify and compare the concentration of different heavy metals in normal and cardiac patients of some zones of sargodha region. trace elements,which show a significant role in healthy as well as in diseased subjects,diverted the attention of scientists to explore the role of these trace elements in the cardiovascular diseases. in this study we compared the levels of zinc,cadmium,copper,nickel,manganese,chromium,and cobalt in hair,nail and plasma samples of different cardiac patients and control subjects. the study was undertaken on equal number of cardiac patients and healthy subjects. in each category 50% was male with age more than or less than 40 years. analysis was done by using atomic absorption spectrophotometer. the mean values of some metals like zn,cu and cr are low in patients rather than normal subjects,while amount of cd,mn,co and ni were seen higher in patients than in control subjects. male patients have (p < 0.05) high values of metals than females; the same is with smoker cardiac patients against non-smokers. on the other hand the patients (male and female) whose age is < 45 have greater values of metals as compare to the cardiac patients of age greater than 45 years. from the results of this study it can be concluded that increase or decrease in heavy metal composition play an adverse effect on the normal function of heart.