Synthesis,characterization and biological activities of a bidentate schiff base ligand: N,N′-Bis(1-phenylethylidene)ethane-1,2-diamine and its transition metals (ii) complexes

Schiff base ligand: n,n′-bis(1-phenylethylidene)ethane-1,2-diamine (l),was derived from acetophenone and ethylenediamine by condensation and its complexes (1-5) were prepared with pb2+,ni2+,co 2+,cu2+ and cd2+ metal ions. their structures were characterized by fab-ms,ir spectra,elemental analyses and molar conductance. the octahedral geometry of the complexes was proposed by electronic spectra and magnetic moment data. the conductivity data showed that the complexes have non-electrolytic nature. the complexes (1-5) have higher in vitro antimicrobial activity than the schiff base ligand (l). in the nuclease activity,the complexes cleave dna as compared to control dna in the presence of h2o2.