Regioselective nucleophilic ring opening of epoxides mediated by novel task-specific ionic liquids; A simple and effective method for production of β-hydroxy azides and β -hydroxy-thiocyanates

One third of worldwide chemical products are produced by catalyzed reactions. most of the imidazolium salts have been introduced as effective and tunable catalysts in many organic transformations. with these regards,in this study,an efficient and environmentally friendly process for the synthesis of β- hydroxy azides and β- hydroxy thiocyanates from epoxides using task-specific ionic liquids (1,1-dimethyl-3,3-ethylenediimidazolium diazide and 1,1-dimethyl-3,3- ethylenediimidazolium dithio-cyanate) as catalyst and reagent in the absence of any organic solvent has been developed. the remarkable features of this procedure are improved the yields,enhanced the reaction rates,high regioselectivity and easy of recyclability of ionic liquids (ils). the recovered ionic liquid can be reused up to three runs without any loss in its activity.