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Phytochemical,antioxidant and antifungal studies on the constituents of lonicera quinquelocularis
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نویسنده
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ali i. ,khan d. ,ali f. ,bibi h. ,malik a.
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منبع
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journal of the chemical society of pakistan - 2013 - دوره : 35 - شماره : 1 - صفحه:139 -143
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چکیده
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Seven secondary metabolites have been isolated for the first time from the chloroform soluble fraction of lonicera quinquelocularis and identified as ferna-7,9(11)-diene-3a,16a-diol (1),lonicerin (log-2) (2),e-p-coumaryl hexacosonoate (3),methyl 2,4-dihydroxy-3,6- dimethylbenzoate (4),7-hydroxycoumarin (5),secologanin dimethylacetal (6) and secologanoside-7- methyl ester (7). their structures were elucidated by uv,ir,ei-ms,hr-eims,fab,and 1 hnmr and 13c-nmr spectral data. all of them were screened for their biological activity; compounds 3 and 5 exhibited significant antioxidant activity whereas compounds 4,6 and 7 showed promising antifungal activity against candida glaberata,microsporum canis and trichophyton longifusus.
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آدرس
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department of chemistry,gomal university, Pakistan, department of chemistry,gomal university, Pakistan, department of chemistry,gomal university, Pakistan, department of chemistry,gomal university, Pakistan, h.e.j.research institute of chemistry,international center for chemical sciences,university of karachi, Pakistan
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Authors
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