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1,3-disubstituted ureas as antiglycating agents
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نویسنده
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perveen s. ,mustafa s. ,khan k.m. ,choudhary m.i.
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منبع
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journal of the chemical society of pakistan - 2013 - دوره : 35 - شماره : 6 - صفحه:1603 -1611
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چکیده
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Twenty one (21) 1,3-disubstituted urea derivatives were screened for their antiglycating potential and some of them displayed promising activity. compound n-butyl-n'-(4-nitrophenyl)urea (6) and nisopropyl-n'-(4-nitrophenyl)urea (18) exhibited excellent activity and could be investigated in search of medicines treating diabetes and associated complications.
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کلیدواژه
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Antiglycation; Diabetes; Structure-activity relationship; Symmetric urea; Unsymmetric urea
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آدرس
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pcsir laboratories complex,shahrah-e-dr. salimuzzaman siddiqui, Pakistan, department of chemistry,university of karachi, Pakistan, h.e.j. research institute of chemistry,international center for chemical and biological sciences,university of karachi, Pakistan, h.e.j. research institute of chemistry,international center for chemical and biological sciences,university of karachi, Pakistan
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Authors
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