>
Fa   |   Ar   |   En
   Stability and enzyme inhibition activities of au nanoparticles using an aqueous extract of clove as a reducing and stabilizing agent  
   
نویسنده hameed a. ,khan i. ,azam a. ,naz s.s. ,khan a. ,saleem m. ,shah m.r. ,islam n.u.
منبع journal of the chemical society of pakistan - 2014 - دوره : 36 - شماره : 3 - صفحه:542 -547
چکیده    Gold nanoparticles (aunps) were synthesized in one pot using aqueous extract of clove buds (cb) to reduce haucl4 and stabilize gold in its atomic form at room temperature. to determine the potential of gold nanoparticles with clove buds (aucb) for in vivo applications,the stability of the nanoparticles was explored as a function of temperature,ph and salt concentration. the suspensions were found to be stable for salt concentrations up to 1 mol/l,temperatures of up to 100 0c and a ph range of 2-13. our results indicate that cb exhibited comparable activities to standards of urease and carbonic anhydrase,but its conjugation to au knocks out the enzyme inhibition activity by about two times. in case of xanthine oxidase activity,cb and its gold au bio-conjugates (aucb) are found to be absolutely inactive.
کلیدواژه Clove buds extract; Comparison; Gold nanoparticles; Stability and enzyme inhibition activities
آدرس institute of chemical sciences,university of peshawar,peshawar, Pakistan, institute of chemical sciences,university of peshawar,peshawar, Pakistan, department of chemistry,university college of science shankar,abdul wali khan,university mardan, Pakistan, institute of chemical sciences,university of peshawar,peshawar, Pakistan, h.e.j. research institute of chemistry,international center for chemical and biological sciences,university of karachi, Pakistan, h.e.j. research institute of chemistry,international center for chemical and biological sciences,university of karachi, Pakistan, h.e.j. research institute of chemistry,international center for chemical and biological sciences,university of karachi, Pakistan, institute of chemical sciences,university of peshawar,peshawar,25120,pakistan,department of pharmacy,sarhad university of science and information technology, Pakistan
 
     
   
Authors
  
 
 

Copyright 2023
Islamic World Science Citation Center
All Rights Reserved