|
|
|
|
Synthesis,characterization and biological evaluation of novel diesters of 4,4'-dihydroxy azoxy benzene with long chain carboxylic acids
|
|
|
|
|
|
|
|
نویسنده
|
shehzadi s. ,siddiqi h.m. ,qasim m.m. ,fawad m. ,manan a. ,khan n. ,saleem s. ,bashir f. ,mirza b.
|
|
منبع
|
journal of the chemical society of pakistan - 2014 - دوره : 36 - شماره : 3 - صفحه:462 -472
|
|
چکیده
|
Synthesis of novel symmetrical azoxy diesters have been prepared by the reaction of 4,4'-dihydroxyazoxy benzene with aliphatic acid halides of varying chain lengths. the synthesized compounds have been characterized by spectral and analytical data. these symmetrical azoxy diesters exhibit good antifungal activity against six fungal strains (mucor species,aspergillus niger,aspergillus flavus,alternaria solani,fusarium solani and aspergillus fumigatus) and antitumor activities while no significant antibacterial activity has been observed. these synthesized compounds are also potent free radical scavengers.
|
|
کلیدواژه
|
4'-Dihydroxyazoxy benzene; Antibacterial; Antifungal; Antitumor; Free radical scavengers; Symmetrical azoxy diesters
|
|
آدرس
|
department of chemistry,quaid-i-azam university, Pakistan, department of chemistry,quaid-i-azam university, Pakistan, department of engineering (division b),cape building, United Kingdom, department of chemistry,quaid-i-azam university, Pakistan, department of chemistry,quaid-i-azam university, Pakistan, department of chemistry,quaid-i-azam university, Pakistan, department of biochemistry,faculty of biological sciences,quaid-i-azam university,islamabad, Pakistan, department of biochemistry,faculty of biological sciences,quaid-i-azam university,islamabad, Pakistan, department of biochemistry,faculty of biological sciences,quaid-i-azam university,islamabad, Pakistan
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Authors
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|