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Chemical constituents and antioxidant activity of fresh leaves of Psidium guajava cultivated in Pakistan
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نویسنده
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begum s. ,ali s.n. ,tauseef s. ,ali s.t. ,hassan s.i. ,siddiqui b.s. ,ahmad a.
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منبع
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journal of the chemical society of pakistan - 2014 - دوره : 36 - شماره : 1 - صفحه:119 -122
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چکیده
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The in vitro antioxidant activities of the methanol extract of fresh leaves of psidium guajava cultivated in pakistan and its different fractions were evaluated using 1,1-diphenyl-2- picrylhydrazyl (dpph) free radical scavenging assay. the methanol extract,main ethyl acetate fraction and its polar sub fraction showed high free radical scavenging activity with ec50 11.72,11.72 and 46.8 μg/ml respectively. the first two values are comparable with that of reference compound ascorbic acid (ec50 9.4 μg/ml). the known antioxidants gallic acid (1),methyl ferulate (2) and methyl p-e-coumarate (3) were isolated from the ethyl acetate insoluble fraction. their structures were identified by mass,1h- and 13c-nmr spectroscopy. compounds 2 and 3 are reported for the first time from the genus psidium.
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کلیدواژه
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DPPH scavenging activity; Gallic acid; Methyl ferulate; Methyl p-E-coumarate; Psidium guajava; Reactive oxygen species
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آدرس
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h.e.j research institute of chemistry,international center for chemical and biological sciences,university of karachi, Pakistan, h.e.j research institute of chemistry,international center for chemical and biological sciences,university of karachi, Pakistan, federal urdu university of arts,science and technology,department of microbiology, Pakistan, department of pharmacognosy,faculty of pharmacy,university of karachi, Pakistan, h.e.j research institute of chemistry,international center for chemical and biological sciences,university of karachi, Pakistan, h.e.j research institute of chemistry,international center for chemical and biological sciences,university of karachi, Pakistan, department of microbiology,university of karachi, Pakistan
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Authors
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