Clerodendrum splendens: A potential source of antimicrobials

The antimicrobial status of the bark and leaves of clerodendrum splendens was evaluated.the inquisition had provided that the leaf and bark of the plant had exhibited maximum antimicrobial potential. the antibacterial activity was significant against s. aureus with the maximum effectiveness of 71 ± 0.6 mm displayed by the petroleum ether extracts of bark. moreover,all the petroleum ether extracts exhibited maximum inhibitory effects against all the bacterial strains. the gram negative strains,i.e. k. pneumoniae,p. aeruginosa and e. coli had provided good to satisfactory results within the range of 20 ± 0.8 mm to 69 ± 0.9 mm. excellent activities were exhibited by leaf and bark extracts against the fungal pathogens with the maximum potential displayed by the petroleum ether extracts of leaf i.e. 57 ± 0.5 mm against a. oryzae. the mic assays were carried out to further authenticate the results obtained by zones of inhibitions. the mic potential exhibited by gram negative bacteria for k. pneumoniae was evaluated to be > 0.032 mg/ml while for the s. aureus was roughly evaluated to be > 0.088. moreover,the mic activity displayed against other gram negative bacterial strains was reported > 0.112 ± 0.7 mg/ml for e. coli and > 0.059 ± 1.0 mg/ml for p. aeruginosa. the mic effectiveness for the fungal strain of a. niger and a. oryzae was evaluated to be 0.118 ± 0.7 mg/ml.