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   Nicotiana plumbaginifolia: A rich antimicrobial and antioxidant source  
   
نویسنده ajaib m. ,fatima s. ,khan k.m. ,perveen s. ,shah s.
منبع journal of the chemical society of pakistan - 2016 - دوره : 38 - شماره : 1 - صفحه:143 -149
چکیده    Antimicrobial and antioxidant activities of plant nicotiana plumbaginifolia viv. were carried out using various techniques. the petroleum ether,chloroform,methanol and aqueous extracts of the n. plumbaginifolia were obtained by maceration technique. the maximum antibacterial potential was exhibited by chloroform leaves extract (76.3 ± 0.3 mm),methanolic root extract (69 ± 0.8 mm) and petroleum ether root extract (67 ± 1.7 mm) against p. aureginosa. methanolic root extract possessed 64 ± 2.3 mm zone of inhibition against e. coli,whereas chloroform root extract displayed 49 ± 0.8 mm against b. subtilis. chloroform root extract showed 48 ±1.2 against s. aureus. the maximum zone of inhibition of antifungal potential was displayed by methanolic extracts of leaves against a. niger (43 ± 0.8 mm) and f. solani (43 ± 1.6 mm). the mic assay was determine for further analysis which showed the mic value of methanolic root extract (0.04 ± 0.1 mg/ml) against e. coli and the mic value was noticed (0.108 ± 0.04 mg/ml) against a. niger by methanolic root extract. antioxidant potential was determined using four methods i.e. [1,1- diphenyl-2-picrylhydrazyl radical (dpph) scavenging activity,total antioxidant activity (taa),total phenolic contents (tpc) and metal chelating activity. the highest value of % dpph was observed 90.56 at 1000 μl concentration in petroleum ether extract. the maximum values of taa,tpc,frap and ftc were 1.352 ± 0.01,1.683 ± 0.09 and 80.66 ± 0.08,respectively.
کلیدواژه Antimicrobial; Antioxidant; MIC; Nicotiana plumbaginifolia
آدرس department of botany,mirpur university of science and technology,ajk, Pakistan, department of botany,government college university,lahore, Pakistan, h. e. j. research institute of chemistry,international center for chemical and biological sciences,university of karachi,karachi, Pakistan, pcsir laboratoires complex,karachi,shahrah-e-dr. salimuzzaman siddiqui,karachi, Pakistan, h. e. j. research institute of chemistry,international center for chemical and biological sciences,university of karachi,karachi, Pakistan
 
     
   
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