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Synthesis,crystal structure and biological evaluation of 5-arylidine derivatives of 3-phenyl-2-(phenylimino)thiazolidin-4-one
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نویسنده
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haroon m. ,akhtar t. ,tahir m.n. ,ali i. ,hameed s.
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منبع
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journal of the chemical society of pakistan - 2017 - دوره : 39 - شماره : 4 - صفحه:614 -618
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چکیده
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Summary: arylidene derivatives of 3-phenyl-2-(phenylimino)thiazolidin-4-ones are prepared by its condensation with respective aromatic aldehydes. the structures of synthesized compounds are established using ftir,13c-nmr,1h-nmr,mass spectrometry. the structure of 5-(furan-2-ylmethylene)-3-phenyl-2-(phenylimino)thiazolidin-4-one (2c) is also confirmed by x-rays crystallography. the compounds were examined for their antibacterial and enzyme inhibitory effects. some of the compounds have shown promising activities.
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کلیدواژه
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Antimicrobial; Arylidene; Thiazolidinones; Thiourea; X-ray crystallography
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آدرس
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department of chemistry,mirpur university of science and technology (must),mirpur-azad-jammu-and-kashmir, Pakistan, department of chemistry,mirpur university of science and technology (must),mirpur-azad-jammu-and-kashmir, Pakistan, department of physics,university of sargodha,punjab, Pakistan, department of biotechnology,mirpur university of science and technology (must),mirpur-azad-jammu-and-kashmir, Pakistan, department of chemistry,quaid-i-azam university,islamabad, Pakistan
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Authors
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