DATforDCEMRI: An R package for deconvolution analysis and visualization of DCE-MRI data

Numerical deconvolution is a powerful mathematical operation that can be used to extract the impulse response function of a linear,time-invariant system. we have found this method to be useful for preliminary analysis of dynamic contrast enhanced magnetic resonance imaging (dce-mri) data,capable of quickly producing voxel-wise parametric maps describing the heterogeneity of contrast agent kinetics over the entire eld of view,typically comprising tens of thousands of voxels. the statistical programming language r is well suited for this type of analysis and when combined with latex,via sweave,allows one to perform all calculations and generate a report with a single script. the purpose of this manuscript is to describe the r package datfordcemri,a deconvolution analysis tool for dce-mri contrast agent concentration vs. time data,which allows the user to perform kinetic deconvolution analysis and visualize/explore the resulting voxel-wise parametric maps and associated data.