Sanon: An R package for stratified analysis with nonparametric covariable adjustment

Kawaguchi,koch,and wang (2011) provide methodology and applications for a stratified mann-whitney estimator that addresses the same comparison between two randomized groups for a strictly ordinal response variable as the van elteren test statistic for randomized clinical trials with strata. the sanon package provides the implementation of the method within the r programming environment. the usage of sanon is illustrated with five examples. the first example is a randomized clinical trial with eight strata and a univariate ordinal response variable. the second example is a randomized clinical trial with four strata,two covariables,and four ordinal response variables. the third example is a crossover design randomized clinical trial with two strata,one covariable,and two ordinal response variables. the fourth example is a randomized clinical trial with seven strata (which are managed as a categorical covariable),three ordinal covariables with missing values,and three ordinal response variables with missing values. the fifth example is a randomized clinical trial with six strata,a categorical covariable with three levels,and three ordinal response variables with missing values. © 2015,american statistical association. all rights reserved.