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   GMCM: Unsupervised clustering and meta-analysis using gaussian mixture copula models  
   
نویسنده bilgrau a.e. ,eriksen p.s. ,rasmussen j.g. ,johnsen h.e. ,dybkær k. ,bøgsted m.
منبع journal of statistical software - 2016 - دوره : 70 - شماره : 0
چکیده    Methods for clustering in unsupervised learning are an important part of the statistical toolbox in numerous scientific disciplines. tewari,giering,and raghunathan (2011) proposed to use so-called gaussian mixture copula models (gmcm) for general unsupervised learning based on clustering. li,brown,huang,and bickel (2011) independently discussed a special case of these gmcms as a novel approach to meta-analysis in highdimensional settings. gmcms have attractive properties which make them highly flexible and therefore interesting alternatives to other well-established methods. however,parameter estimation is hard because of intrinsic identifiability issues and intractable likelihood functions. both aforementioned papers discuss similar expectation-maximization-like algorithms as their pseudo maximum likelihood estimation procedure. we present and discuss an improved implementation in r of both classes of gmcms along with various alternative optimization routines to the em algorithm. the software is freely available in the r package gmcm. the implementation is fast,general,and optimized for very large numbers of observations. we demonstrate the use of package gmcm through different applications. © 2016,american statistical association. all rights reserved.
کلیدواژه C++; Clustering; Copulas; Evidence aggregation; GMCM; High-dimensional experiments; idr; Meta-analysis; p value combination; R; Rcpp; Reproducibility; Unsupervised learning
آدرس aalborg university, Denmark, aalborg university, Denmark, aalborg university, Denmark, aalborg university hospital, Denmark, aalborg university hospital, Denmark, aalborg university hospital, Denmark
 
     
   
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