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Treatment failure and costs in patients with methicillin-resistant Staphylococcus aureus (MRSA) skin and soft tissue infections: A south Texas ambulatory research network (STARNet) study
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نویسنده
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labreche m.j. ,lee g.c. ,attridge r.t. ,mortensen e.m. ,koeller j. ,du l.c. ,nyren n.r. ,treviño l.b. ,treviño s.b. ,peña j. ,mann m.w. ,muñoz a. ,marcos y. ,rocha g. ,koretsky s. ,esparza s. ,finnie m. ,dallas s.d. ,parchman m.l. ,frei c.r.
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منبع
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journal of the american board of family medicine - 2013 - دوره : 26 - شماره : 5 - صفحه:508 -517
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چکیده
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Objective: to measure the incidence of treatment failure and associated costs in patients with methicillin-resistant staphylococcus aureus skin and soft tissue infections (sstis). methods: this was a prospective,observational study in 13 primary care clinics. primary care providers collected clinical data,wound swabs,and 90-day follow-up information. patients were considered to have moderate or complicated sstis if they had a lesion ≥5 cm in diameter or diabetes mellitus. treatment failure was evaluated within 90 days of the initial visit. cost estimates were obtained from federal sources. results: overall,treatment failure occurred in 21% of patients (21 of 98) at a mean additional cost of $1,933.71 per patient. in a subgroup analysis of patients who received incision and drainage,those with moderate or complicated sstis had higher rates of treatment failure than those with mild or uncomplicated sstis (36% vs. 10%; p = .04). conclusions: one in 5 patients presenting to a primary care clinic for a methicillin-resistant s. aureus ssti will likely require additional interventions at an associated cost of almost $2,000 per patient. baseline risk stratification and new treatment approaches are needed to reduce treatment failures and costs in the primary care setting.
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کلیدواژه
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Antibiotics; Cost of illness; Epidemiology; Infectious diseases; Practice-based research; Primary health care
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آدرس
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division of pharmacotherapy,college of pharmacy,university of texas at austin,austin,united states,pharmacotherapy education and research center,school of medicine,university of texas health science center at san antonio,7703 floyd curl dr.,san antonio,tx 78229-3900, United States, division of pharmacotherapy,college of pharmacy,university of texas at austin,austin,united states,pharmacotherapy education and research center,school of medicine,university of texas health science center at san antonio,7703 floyd curl dr.,san antonio,tx 78229-3900, United States, feik school of pharmacy,university of the incarnate word,san antonio, United States, division of general internal medicine,va north texas health care system,dallas,united states,department of internal medicine,university of texas southwestern medical center,dallas,united states,department of internal medicine clinical sciences,university of texas southwestern medical center,dallas, United States, division of pharmacotherapy,college of pharmacy,university of texas at austin,austin,united states,pharmacotherapy education and research center,school of medicine,university of texas health science center at san antonio,7703 floyd curl dr.,san antonio,tx 78229-3900, United States, south texas ambulatory research network,university of texas health science center,san antonio, United States, south texas ambulatory research network,university of texas health science center,san antonio, United States, south texas ambulatory research network,university of texas health science center,san antonio, United States, south texas ambulatory research network,university of texas health science center,san antonio, United States, south texas ambulatory research network,university of texas health science center,san antonio, United States, south texas ambulatory research network,university of texas health science center,san antonio, United States, south texas ambulatory research network,university of texas health science center,san antonio, United States, south texas ambulatory research network,university of texas health science center,san antonio, United States, south texas ambulatory research network,university of texas health science center,san antonio, United States, south texas ambulatory research network,university of texas health science center,san antonio, United States, south texas ambulatory research network,university of texas health science center,san antonio, United States, south texas ambulatory research network,university of texas health science center,san antonio, United States, school of health professions,clinical laboratory sciences,university of texas health science center,san antonio, United States, maccoll center for health care innovation,group health research institute,group health cooperative,seattle,wa, United States, division of pharmacotherapy,college of pharmacy,university of texas at austin,austin,united states,pharmacotherapy education and research center,school of medicine,university of texas health science center at san antonio,7703 floyd curl dr.,san antonio,tx 78229-3900, United States
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Authors
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