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Acute urinary morbidity after a permanent 125I implantation for localized prostate cancer
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نویسنده
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ohga s. ,nakamura k. ,shioyama y. ,tatsugami k. ,sasaki t. ,nonoshita t. ,yoshitake t. ,asai k. ,hirata h. ,naito s. ,honda h.
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منبع
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journal of radiation research - 2014 - دوره : 55 - شماره : 6 - صفحه:1178 -1183
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چکیده
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We evaluated the predictive factors of acute urinary morbidity (aum) after prostate brachytherapy. from november 2005 to january 2007,62 patients with localized prostate cancer were treated using brachytherapy. the 125iodine (125i) seed-delivering method was a modified peripheral pattern. the prescribed dose was 144 gy. urinary morbidity was scored at 3 months after implantation. the clinical and treatment parameters were analysed for correlation with aum. in particular,in this study,du90 (the minimal dose received by 90% of the urethra),dup90 (the minimal dose received by 90% of the proximal half of the urethra on the bladder side) and dud90 (the minimal dose received by 90% of the distal half of the urethra on the penile side) were analysed. we found that 43 patients (69.4%) experienced acute urinary symptoms at 3 months after implantation. of them,40 patients had grade 1 aum,one patient had grade 2 pain,and two patients had grade 2 urinary frequency. none of the patients had ≥grade 3. univariate and multivariate analysis revealed that du90 and dup90 were significantly correlated with aum. in this study,du90 and dup90 were the most significant predictors of aum after prostate brachytherapy. © the author 2014. published by oxford university press on behalf of the japan radiation research society and japanese society for radiation oncology.
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کلیدواژه
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125I implantation; Acute urinary morbidity; Prostate cancer
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آدرس
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department of clinical radiology,graduate school of medical sciences,kyushu university,3-1-1 maidashi,higashi-ku,fukuoka, Japan, department of clinical radiology,graduate school of medical sciences,kyushu university,3-1-1 maidashi,higashi-ku,fukuoka, Japan, kyushu international heavy ion beam cancer treatment center,415 harakoga,tosu,saga, Japan, department of urology,graduate school of medical sciences,kyushu university,3-1-1 maidashi,higashi-ku,fukuoka, Japan, department of clinical radiology,graduate school of medical sciences,kyushu university,3-1-1 maidashi,higashi-ku,fukuoka, Japan, department of clinical radiology,graduate school of medical sciences,kyushu university,3-1-1 maidashi,higashi-ku,fukuoka, Japan, department of clinical radiology,graduate school of medical sciences,kyushu university,3-1-1 maidashi,higashi-ku,fukuoka, Japan, department of clinical radiology,graduate school of medical sciences,kyushu university,3-1-1 maidashi,higashi-ku,fukuoka, Japan, school of health sciences,faculty of medicine,kyushu university,3-1-1 maidashi,higashi-ku,fukuoka, Japan, department of urology,graduate school of medical sciences,kyushu university,3-1-1 maidashi,higashi-ku,fukuoka, Japan, department of clinical radiology,graduate school of medical sciences,kyushu university,3-1-1 maidashi,higashi-ku,fukuoka, Japan
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Authors
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