>
Fa   |   Ar   |   En
   Margin estimation and disturbances of irradiation field in layer-stacking carbon-ion beams for respiratory moving targets  
   
نویسنده tajiri s. ,tashiro m. ,mizukami t. ,tsukishima c. ,torikoshi m. ,kanai t.
منبع journal of radiation research - 2017 - دوره : 58 - شماره : 6 - صفحه:840 -848
چکیده    Carbon-ion therapy by layer-stacking irradiation for static targets has been practised in clinical treatments. in order to apply this technique to a moving target,disturbances of carbon-ion dose distributions due to respiratory motion have been studied based on the measurement using a respiratory motion phantom,and the margin estimation given by the square root of the summation √internal margin2 + setup margin2 has been assessed. we assessed the volume in which the variation in the ratio of the dose for a target moving due to respiration relative to the dose for a static target was within 5%. the margins were insufficient for use with layer-stacking irradiation of a moving target,and an additional margin was required. the lateral movement of a target converts to the range variation,as the thickness of the range compensator changes with the movement of the target. although the additional margin changes according to the shape of the ridge filter,dose uniformity of 5% can be achieved for a spherical target 93 mm in diameter when the upward range variation is limited to 5 mm and the additional margin of 2.5mm is applied in case of our ridge filter. dose uniformity in a clinical target largely depends on the shape of the mini-peak as well as on the bolus shape. we have shown the relationship between range variation and dose uniformity. in actual therapy,the upper limit of target movement should be considered by assessing the bolus shape. © the author 2017.
کلیدواژه Carbon-ion; Gated irradiation; Layer-stacking; Margin; Respiratory motion
آدرس department of heavy ion beam medical physics and biology,gunma university graduate school of medicine,3-39-22 showa-machi,maebashi,gunma,371-8511,japan,mitsubishi electric corporation,1-1-2,wadasaki-cho,hyogo-ku,kobe,652-8555, Japan, research program for heavy ion therapy,gunma university initiative for advanced research,3-39-22 showa-machi,maebashi,gunma,japan,gunma university heavy ion medical center,3-39-22 showa-machi,maebashi,gunma, Japan, mitsubishi electric corporation,1-1-2,wadasaki-cho,hyogo-ku,kobe,652-8555, Japan, mitsubishi electric corporation,1-1-2,wadasaki-cho,hyogo-ku,kobe,652-8555, Japan, department of heavy ion beam medical physics and biology,gunma university graduate school of medicine,3-39-22 showa-machi,maebashi,gunma,371-8511,japan,gunma university heavy ion medical center,3-39-22 showa-machi,maebashi,gunma, Japan, department of heavy ion beam medical physics and biology,gunma university graduate school of medicine,3-39-22 showa-machi,maebashi,gunma,371-8511,japan,gunma university heavy ion medical center,3-39-22 showa-machi,maebashi,gunma, Japan
 
     
   
Authors
  
 
 

Copyright 2023
Islamic World Science Citation Center
All Rights Reserved