>
Fa   |   Ar   |   En
   Pharmacogenetics of antidepressant response  
   
نویسنده porcelli s. ,drago a. ,fabbri c. ,gibiino s. ,calati r. ,serretti a.
منبع journal of psychiatry and neuroscience - 2011 - دوره : 36 - شماره : 2 - صفحه:87 -113
چکیده    Personalized medicine - the adaptation of therapies based on an individual's genetic and molecular profile - is one of the most promising aspects of modern medicine. the identification of the relation between genotype and drug response,including both the therapeutic effect and side effect profile,is expected to deeply affect medical practice. in this paper,we review the current knowledge about the genes related to antidepressant treatment response and provide methodologic proposals for future studies. we have mainly focused on genes associated with pharmacodynamics,for which a list of promising genes has been identified despite some inconsistency across studies. we have also synthesized the main results for pharmacokinetic genes,although so far they seem less relevant than those for pharmaco dynamic genes. we discuss possible reasons for these inconsistent findings and propose new study designs. © 2011 canadian medical association.
آدرس institute of psychiatry,university of bologna,bologna, Italy, institute of psychiatry,university of bologna,bologna, Italy, institute of psychiatry,university of bologna,bologna, Italy, institute of psychiatry,university of bologna,bologna, Italy, institute of psychiatry,university of bologna,bologna, Italy, institute of psychiatry,university of bologna,bologna, Italy
 
     
   
Authors
  
 
 

Copyright 2023
Islamic World Science Citation Center
All Rights Reserved