Duodenocutaneous fistula in rats as a model for “wound healing-therapy” in ulcer healing: the effect of pentadecapeptide BPC 157,L-nitro-arginine methyl ester and L-arginine

While very rarely reported,duodenocutanenous fistula research might alter the duodenal ulcer disease background and therapy. our research focused on rat duodenocutaneous fistulas,therapy,stable gastric pentadecapeptide bpc 157,an anti-ulcer peptide that healed other fistulas,nitric oxide synthase-substrate l-arginine,and nitric oxide synthase-inhibitor l-nitro-arginine methyl ester (l-name). the hypothesis was,duodenal ulcer-healing,like the skin ulcer,using the successful bpc 157,with nitric oxide-system involvement,the wound healing-therapy