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Atrial natriuretic peptide and brain natriuretic peptide changes after epicardial percutaneous left atrial appendage suture ligation using lariat device
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نویسنده
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bartus k. ,podolec j. ,lee r.j. ,kapelak b. ,sadowski j. ,bartus m. ,oles k. ,ceranowicz p. ,trabka r. ,litwinowicz r.
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منبع
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journal of physiology and pharmacology - 2017 - دوره : 68 - شماره : 1 - صفحه:117 -123
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چکیده
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Percutaneous left atrial appendage closure is an alternative treatment for stroke and systemic thromboembolism risk reduction in non-valvular atrial fibrillation (af). however,the neurohormonal impact of epicardial exclusion of the left atrial appendage (laa) with the lariat procedure is unknown. evaluation of changes in atrial natriuretic peptide (anp) and brain natriuretic peptide (bnp) levels in af patients underwent percutaneous laa suture ligation. sixty six patients underwent successfully percutaneous laa suture ligation using lariat device. the level of anp and bnp was measured before and 3 months after procedure. mean anp level before procedure was 249 ± 77 pg/ml (range from 95 pg/ml to 503 pg/ml) and mean bnp level was 481 ± 517 pg/ml (range from 34 pg/ml to 2508 pg/ml). three months after procedure mean anp level was 249 ± 79 pg/ml (range from 98 pg/ml to 492 pg/ml) and mean bnp level was 495 ± 526 pg/ml (range from 52 pg/ml to 2420 pg/ml). at 3 months follow up after percutaneous laa suture ligation there were no significant differences in anp and bnp levels. © 2017,polish physiological society. all rights reserved.
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کلیدواژه
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Atrial fibrillation; Atrial natriuretic peptide; Brain natriuretic peptide; Left atrial appendage
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آدرس
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department of cardiovascular surgery and transplantology,jagiellonian university,collegium medicum,john paul ii hospital,cracow, Poland, department of interventional cardiology,jagiellonian university,collegium medicum,john paul ii hospital,cracow, Poland, cardiovascular research institute,university of california san francisco,san francisco,ca,united states,department of medicine,university of california san francisco,san francisco,ca,united states,institute for regeneration medicine,university of california san francisco,san francisco,ca, United States, department of cardiovascular surgery and transplantology,jagiellonian university,collegium medicum,john paul ii hospital,cracow, Poland, department of cardiovascular surgery and transplantology,jagiellonian university,collegium medicum,john paul ii hospital,cracow, Poland, department of experimental pharmacology,jagiellonian university medical college,cracow, Poland, department of cardiovascular surgery and transplantology,jagiellonian university,collegium medicum,john paul ii hospital,cracow, Poland, department of physiology,jagiellonian university medical college,cracow, Poland, department of rehabilitation,jagiellonian university medical college,cracow, Poland, department of cardiovascular surgery and transplantology,jagiellonian university,collegium medicum,john paul ii hospital,cracow, Poland
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Authors
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