>
Fa   |   Ar   |   En
   pitfalls in quantitative myocardial pet perfusion ii: arterial input function  
   
نویسنده bui linh ,kitkungvan danai ,roby amanda e. ,nguyen tung t. ,gould k. lance
منبع journal of nuclear cardiology - 2020 - دوره : 27 - شماره : 2 - صفحه:397 -409
چکیده    We aimed to define the impact of variable arterial input function on myocardial perfusion severity that misguide interventional decisions and relates to limited capacity of 3d pet for high-count arterial input function of standard bolus r-82. we used ge discovery-st 16 slice pet-ct, serial 2d and 3d acquisitions of variable rb-82 dose in a dynamic circulating arterial function model, static resolution and uniformity phantoms, and in patients with dipyridamole stress to quantify per-pixel rest and stress cc·min−1·g−1, cfr and cfc with (+) and (−) 10% simulated change in arterial input. for intermediate, border zone severity of stress perfusion, cfr and cfc comprising 7% of 3987 cases, simulated arterial input variability of ± 10% cause over or underestimation of perfusion severity altering interventional decisions. in phantom tests, current 3d pet has capacity for quantifying high activity of arterial input and high-count per-pixel values of perfusion metrics per artery or branches. accurate, reproducible arterial input function is essential for at least 7% of patients at thresholds of perfusion severity for optimally guiding interventions and providing high-activity regional per-pixel perfusion metrics by 3d pet for displaying complex quantitative perfusion readily understood (“owned”) by interventionalists to guide procedures.
کلیدواژه quantitative myocardial perfusion ,cardiac pet
آدرس mcgovern medical school and memorial hermann hospital, division of cardiology and weatherhead pet center for preventing atherosclerosis, department of medicine, usa, mcgovern medical school and memorial hermann hospital, division of cardiology and weatherhead pet center for preventing atherosclerosis, department of medicine, usa, mcgovern medical school and memorial hermann hospital, weatherhead pet center for preventing atherosclerosis, usa, university of texas, weatherhead pet center, mcgovern medical school, programming and data management, usa, university of texas health science center at houston, weatherhead pet center for preventing and reversing atherosclerosis, mcgovern medical school, usa
 
     
   
Authors
  
 
 

Copyright 2023
Islamic World Science Citation Center
All Rights Reserved