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upper reference limits of transient ischemic dilation ratio for different protocols on new-generation cadmium zinc telluride cameras: a report from refine spect registry
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نویسنده
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hu lien-hsin ,sharir tali ,miller robert j. h. ,einstein andrew j. ,fish mathews b. ,ruddy terrence d. ,dorbala sharmila ,carli marcelo di ,kaufmann philipp a. ,sinusas albert j. ,miller edward j. ,bateman timothy m. ,betancur julian ,germano guido ,liang joanna x. ,commandeur frederic ,azadani peyman n. ,gransar heidi ,otaki yuka ,tamarappoo balaji k. ,dey damini ,berman daniel s. ,slomka piotr j.
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منبع
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journal of nuclear cardiology - 2020 - دوره : 27 - شماره : 4 - صفحه:1180 -1189
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چکیده
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Upper reference limits for transient ischemic dilation (tid) have not been rigorously established for cadmium-zinc-telluride (czt) camera systems. we aimed to derive tid limits for common myocardial perfusion imaging protocols utilizing a large, multicenter registry (refine spect). one thousand six hundred and seventy-two patients with low likelihood of coronary artery disease with normal perfusion findings were identified. images were processed with quantitative perfusion spect software (cedars-sinai medical center, los angeles, ca). non-attenuation-corrected, camera-, radiotracer-, and stress protocol-specific tid limits in supine position were derived from 97.5th percentile and mean + 2 standard deviations (sd). reference limits were compared for different solid-state cameras (d-spect vs. discovery), radiotracers (technetium-99m-sestamibi vs. tetrofosmin), different types of stress (exercise vs. four different vasodilator-based protocols), and different vasodilator-based protocols. tid measurements did not follow gaussian distribution in six out of eight subgroups. tid limits ranged from 1.18 to 1.52 (97.5th percentile) and 1.18 to 1.39 (mean + 2sd). no difference was noted between d-spect and discovery cameras (p = 0.71) while differences between exercise and vasodilator-based protocols (adenosine, regadenoson, or regadenoson-walk) were noted (all p < 0.05). we used a multicenter registry to establish camera-, radiotracer-, and protocol-specific upper reference limits of tid for supine position on czt camera systems. reference limits did not differ between d-spect and discovery camera.
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کلیدواژه
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coronary artery disease ,single-photon emission computed tomography ,myocardial perfusion imaging ,perfusion agents ,vasodilators ,image analysis
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آدرس
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cedars-sinai medical center, department of imaging (division of nuclear medicine), usa. taipei veterans general hospital, department of nuclear medicine, taiwan, assuta medical center, department of nuclear cardiology, israel. ben gurion university of the negev, israel, cedars-sinai medical center, department of imaging (division of nuclear medicine), usa, columbia university irving medical center and new york-presbyterian hospital, division of cardiology, department of medicine, and department of radiology, usa, sacred heart medical center, oregon heart and vascular institute, usa, university of ottawa heart institute, division of cardiology, canada, brigham and women’s hospital, division of nuclear medicine and molecular imaging, department of radiology, usa, brigham and women’s hospital, division of nuclear medicine and molecular imaging, department of radiology, usa, university hospital zurich, department of nuclear medicine, switzerland, yale university school of medicine, section of cardiovascular medicine, department of internal medicine, usa, yale university school of medicine, section of cardiovascular medicine, department of internal medicine, usa, cardiovascular imaging technologies llc, usa, cedars-sinai medical center, department of imaging (division of nuclear medicine), usa, cedars-sinai medical center, department of imaging (division of nuclear medicine), usa, cedars-sinai medical center, department of imaging (division of nuclear medicine), usa, cedars-sinai medical center, department of imaging (division of nuclear medicine), usa, cedars-sinai medical center, department of imaging (division of nuclear medicine), usa, cedars-sinai medical center, department of imaging (division of nuclear medicine), usa, cedars-sinai medical center, department of imaging (division of nuclear medicine), usa, cedars-sinai medical center, department of imaging (division of nuclear medicine), usa, cedars-sinai medical center, department of imaging (division of nuclear medicine), usa, cedars-sinai medical center, department of imaging (division of nuclear medicine), usa, cedars-sinai medical center, department of imaging (division of nuclear medicine), usa
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Authors
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