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   myocardial blood flow quantitation in patients with congestive heart failure: head-to-head comparison between rapid-rotating gantry spect and czt spect  
   
نویسنده ma rongzheng ,wang lei ,wu dayong ,wang meng ,sun xiaoxin ,hsu bailing ,fang wei
منبع journal of nuclear cardiology - 2020 - دوره : 27 - شماره : 6 - صفحه:2287 -2302
چکیده    Recently, the feasibility of myocardial blood flow (mbf) quantitation using rapid-rotating gantry (rrg) and cadmium–zinc–telluride (czt) spect cameras has been demonstrated. we compared mbf quantitation using these two camera systems. twenty patients with congestive heart failure (chf) and 20 patients without chf (non-chf) were included. on two consecutive days, dynamic spect imaging was performed after a bolus injection of 20 mci of 99mtc-sestamibi (mibi) with rrg-spect and list-mode acquisition with czt-spect. all dynamic spect images were reconstructed with full physical corrections, corrections for ventricular spillover and partial volume effect, using one-tissue kinetic modeling. resting mbf converted from k1 was then corrected for mibi extraction fraction and adjusted for rate-pressure product. in both patient groups, there was no significant difference between resting mbf values measured with rrg-spect and czt-spect systems (p = 0.06, p = 0.2 respectively). for chf patients, linear regression (lr) was y(rrg) = 1.0412x (czt) (r = 0.97) with a small systemic difference (δ = 0.03 ml·min−1·g−1, 95% ci − 0.11 to 0.20) by bland–altman analysis. for non-chf patients, lr was y(rrg) = 1.025x (czt) (r = 0.89) with also small systemic difference (δt= 0.02 ml·min−1·g−1, 95% ci − 0.14 to 0.19) in ba analysis. physical corrections along with other image corrections can provide comparable mbf quantitations in both chf and non-chf patients, regardless of the type of spect systems used.
کلیدواژه spect myocardial blood flow quantitation ,rapid-rotating spect ,czt spect ,congestive heart failure ,physical corrections ,corrections of left and right ventricle spillovers ,correction of 99mtc-sestamibi extraction fraction
آدرس chinese academy of medical sciences and peking union medical college, fuwai hospital, national center for cardiovascular diseases, department of nuclear medicine, china, chinese academy of medical sciences and peking union medical college, fuwai hospital, national center for cardiovascular diseases, department of nuclear medicine, china, chinese academy of medical sciences and peking union medical college, fuwai hospital, national center for cardiovascular diseases, department of nuclear medicine, china, chinese academy of medical sciences and peking union medical college, fuwai hospital, national center for cardiovascular diseases, department of nuclear medicine, china, chinese academy of medical sciences and peking union medical college, fuwai hospital, national center for cardiovascular diseases, department of nuclear medicine, china, university of missouri-columbia, nuclear science and engineering institute, usa. national yang-ming university, department of biomedical imaging and radiological sciences, taiwan, chinese academy of medical sciences and peking union medical college, fuwai hospital, national center for cardiovascular diseases, department of nuclear medicine, china
 
     
   
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