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gated spect myocardial perfusion imaging with cadmium-zinc-telluride detectors allows real-time assessment of dobutamine-stress-induced wall motion abnormalities
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نویسنده
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nkoulou rene ,wolfrum mathias ,pazhenkottil aju p. ,fiechter michael ,buechel ronny r. ,gaemperli oliver ,kaufmann philipp a.
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منبع
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journal of nuclear cardiology - 2019 - دوره : 26 - شماره : 5 - صفحه:1734 -1742
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چکیده
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Left ventricular (lv) ejection fraction (ef) during high dobutamine stress (hd) by real-time gated-spect myocardial perfusion imaging (mpi) on a cadmium-zinc-telluride (czt) gamma camera was validated versus cardiac magnetic resonance imaging (cmr). after injecting 99mtc-tetrofosmin (320 mbq) in 50 patients (mean age 64 +/− 11 years), ef at rest and post-stress as well as relevant changes in ef at hd (δef ≥ 5%) were assessed. czt and cmr rest ef values yielded an excellent correlation and agreement (r = 0.96; p < 0.001; bland–altman limits of agreement (ba): + 0 to 14.8%). hd ef acquisition was feasible using czt and correlated better to hd cmr ef than did post-stress czt ef (r = 0.85 vs 0.76, respectively, all p < 0.001). agreement in δef detection between hd cmr and immediate post-stress czt (reflecting standard acquisition using conventional spect camera unable to scan during stress) was 45%, while this increased to 85% with real-time hd czt scan. real-time ultrafast dobutamine gated-spect mpi with a czt device is feasible and provides accurate measurements of hd lv performance.
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کلیدواژه
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cadmium-zinc-telluride detectors gamma camera ,dobutamine-stress ,wall motion abnormalities
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آدرس
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university hospital zurich, department of nuclear medicine, switzerland. university hospital geneva, department of cardiology, switzerland, university hospital zurich, department of nuclear medicine, switzerland, university hospital zurich, department of nuclear medicine, switzerland, university hospital zurich, department of nuclear medicine, switzerland, university hospital zurich, department of nuclear medicine, switzerland, university hospital zurich, department of nuclear medicine, switzerland, university hospital zurich, department of nuclear medicine, switzerland
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Authors
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