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Association between non-perfusion parameters and presence of ischemia in gated-SPECT myocardial perfusion imaging studies
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نویسنده
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Peix Amalia ,Cabrera Lázaro O. ,Padrón Kenia ,Rodríguez Lydia ,Fernández Jesús ,López Giselle ,Carrillo Regla ,Mena Erick ,Fernández Yoel ,Dondi Maurizio ,Páez Diana
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منبع
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journal of nuclear cardiology - 2018 - دوره : 25 - شماره : 2 - صفحه:609 -615
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چکیده
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Combined assessment of perfusion and function improves diagnostic and prognostic power of gated-spect in patients with coronary artery disease. the aim of this study was to investigate whether the presence of stress-induced ischemia is associated with abnormal resting left ventricular (lv) function and intraventricular dyssynchrony. gated-spect myocardial perfusion imaging (mpi) at rest and 15 min post-stress was performed in 101 patients, who were divided into three groups: those with stress-induced ischemia (group 1, n = 58), those with normal scans (group 2, n = 28), and those with scar but no ischemia (group 3, n = 15). more extensive perfusion defects were found in patients of groups 1 and 3 [summed stress score (sss): 13 ± 8 and 21 ± 9, respectively]. in group 2, the mean sss was 1.5. the mean change in lv ejection fraction (lvef at stress − lvef at rest) was higher in group 1 v. group 2 patients: −5.54% ± 6.24% vs −2.46% ± 5.56%, p = 0.02. group 3 patients also had higher values, similar to group 1: −6.47% ± 8.82%. patients with ischemia had almost 50% higher end-diastolic volumes than patients with normal mpi. similarly, end-systolic volumes were almost twice as high in this group (p < 0.0001). in addition, the histogram bandwidth, a measure of intraventricular dyssynchrony, was greater in group 1. baseline differences in left ventricular volumes and degree of dyssynchrony are associated with inducible ischemia on stress testing in a gated-spect mpi. stress-induced ischemia increases the degree of intraventricular dyssynchrony.
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کلیدواژه
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Myocardial perfusion imaging ,left ventricular ejection fraction ,intraventricular synchrony ,ischemia ,gated-SPECT
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آدرس
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Institute of Cardiology, Nuclear Medicine Department, Cuba, Institute of Cardiology, Cuba, Institute of Cardiology, Cuba, Institute of Cardiology, Cuba, Institute of Cardiology, Cuba, Institute of Cardiology, Cuba, Institute of Cardiology, Cuba, Institute of Cardiology, Cuba, Institute of Cardiology, Cuba, International Atomic Energy Agency, Nuclear Medicine and Diagnostic Imaging Section, Division of Human Health, Austria, International Atomic Energy Agency, Nuclear Medicine and Diagnostic Imaging Section, Division of Human Health, Austria
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Authors
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