Comparison of biventricular ejection fractions using cadmium-zinc-telluride SPECT and planar equilibrium radionuclide angiography

We compared biventricular ejection fractions (efs) from gated blood-pool single-photon emission computed tomography (spect) using a cadmium-zinc-telluride camera (czt-spect) with planar equilibrium radionuclide angiography (erna) using a nai gamma camera (nai-planar). we also evaluated whether imaging time can be reduced without compromising image quality using the czt camera. forty-eight patients underwent nai-planar and czt-spect on the same day. czt-spect datasets were re-projected at an lao orientation similar to erna acquisition, forming czt-repro planar datasets. the resulting biventricular volumetric measurements and efs were compared. lvef calculated from czt-spect and czt-repro correlated better with nai-planar (r = 0.93 and 0.99, respectively) than rvef (r = 0.76 and 0.82, respectively). excellent intra-class correlation and low bias in intra-observer comparisons were observed for the biventricular efs derived from three datasets. a wider limit of agreement in czt-spect-derived lvefs, lower correlation and significant bias for nai-planar, and czt-repro-derived rvefs was found in the inter-observer analyses. nonetheless, the imaging time can be reduced to 4 minutes without increasing variability in efs using the czt camera (p = ns). lvefs calculated from czt-spect and czt-repro correlated well with nai-planar. czt camera reduce imaging time while preserving image quality in the assessment of biventricular efs.