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Event related potentials and cognitive evaluation in Wilson's disease with and without neurological manifestation [Nörolojik bulgulari{dotless} olan ya da olmayan wilson hastali{dotless}g̈i{dotless}'nda olaya bag̈li{dotless} potansiyeller ve bilişsel deg̈erlendirme]
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نویسنده
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günther p. ,villmann t. ,hermann w.
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منبع
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journal of neurological sciences [turkish] - 2011 - دوره : 28 - شماره : 1 - صفحه:79 -85
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چکیده
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A cognitive impairment profile with the 'structured interview for the diagnosis of dementia of the alzheimer type,multi-infarct dementia,and dementias of other etiology' (sidam) including mini-mental state examination (mmse) as well as auditory evoked p300 potentials were performed in 35 adult patients with wilson's disease. patients with a neurological course of the disease by trend showed lower amplitudes,delayed latencies of p300 and lower values in the cognitive tests but all median results were still at a normal range without correlation of cognitive decline to the extent of neurological impairment. the possibility of mild cognitive impairment in wilson's disease is discussed.
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کلیدواژه
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Cognitive impairment; Event related potentials; P300; Wilson's disease
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آدرس
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leipzig university,department of neurology, Germany, university of applied sciences,department of mathematics, Germany, paracelsus klinik,department of neurology, Germany
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Authors
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