Single-fiber EMG in Meniere's disease [Meniere hastali{dotless}ǧi{dotless}nda teklif EMG]

Objective: to assess neuromuscular transmission (nmt) in patients with meniere's disease (md),in which the precise etiology is unknown and a channelopathy hypothesis has been proposed methods: single fiber electromyography (sfemg) during voluntary contraction of the extansor digitorum communis muscle,nerve conduction studies of upper and lower extremities and concentric needle electromyography of the extensor digitorum communis were performed on 20 patients (13 female,7 male) with md and 12 age-matched normal controls (4 female,8 male). mean jitter value was calculated for each subject and was compared with the values recorded from normal controls. results: the mean jitter values of the md group were not different from the mean jitter values of normal control subjects. conclusion: even though our findings are not consistent with neuromuscular conduction defect,this doesn't exclude presence of channelopathy in the pathogenesis of md.