Acute lithium neurotoxicity: Clinical and electrophysiological evaluation of four cases [Lityum nörotoksisitesi: 4 olgunun klinik ve elekrofizyolojik deǧerlendirilmesi]

Lithium is one of the first choice agents for long-term prophylaxis and the treatment of acute episodes of bipolar disorders. because of its narrow therapeutic range and the common undesirable side effects,using lower lithium dosages with lower lithium serum levels are preferred treatment regimen especially for maintenance treatment. concomitant drug using (especially neuroleptics),underlying infections and metabolic causes; such as dehydration and renal insufficiency take place in factors facilitating the development of toxicity. lithium intoxication is distinguished in three different patterns as acute