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β-Tubulin mRNA expression profiles during long-term memory formation in classically conditioned C. elegans [Klasik koşullanmi{dotless}ş C. elegans'ta uzun-dönemli bellek oluşumu si{dotless}rasi{dotless}nda β-tübülin mRNA i̇fadelenme profilleri]
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نویسنده
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erdogan m. ,sahin e.
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منبع
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journal of neurological sciences [turkish] - 2013 - دوره : 30 - شماره : 2 - صفحه:296 -304
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چکیده
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We report on the mrna expression profiles of β-tubulin genes in caenorhabditis elegans during the process of classical conditioning,a type of associative learning. in this research,based on the model that suggests the formation of new synaptic connections for long-term memory storage by means of cytoskeletal rearrangement,we measure the expressional changes on the β-tubulin mrna levels via quantitative real-time pcr. using this method,we find that β-tubulin mrna levels do not significantly change in c. elegans during classical conditioning and long-term memory formation process.
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کلیدواژه
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C. elegans; Classical conditioning; Learning; Long-term memory; Memory; Tubulin
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آدرس
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institute of materials science and nanotechnology,bilkent university, Turkey, department of microbiology and immunology,school of medicine, United States
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Authors
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