Effects of statin treatment on early outcomes and restenosis after carotid stenting [Statin tedavisinin karotis stentleme sonrası erken sonuçlar ve restenoza etkisi]

Introduction: the benefits of statin treatment in patients undergoing carotid angioplasty with stenting (cas) have not been well established. this study aimed to determine the short-term effect of statins on periprocedural cerebrovascular complications and on the restenosis rate following cas.methods: the medical records of 59 consecutive patients who underwent cas from december 2010 to december 2012 were retrospectively evaluated. the national institutes of health stroke scale (nihss) and modified rankin scale (mrs) scores were recorded before and after the cas,and the periprocedural cerebrovascular complications and restenosis rates were also recorded.results: of the 59 cas patients included in the study,74.6% were male (mean age,67.3 years; 84.7% symptomatic),and 27 (46.6%) patients were actually undergoing statin treatment. minor stroke developed in three patients undergoing statin treatment prior to cas (p=0.09). major stroke developed within 24 h after cas in one patient who did not undergo statin treatment prior to cas (p=0.54). twenty-two patients had follow-up examinations,and only one patient who did not undergo statin treatment developed remarkable restenosis (p=0.219).discussion: no significant associations were observed between the patients who underwent statin treatment prior to cas and experiencing periprocedural cerebrovascular complications or restenosis. future studies with larger patient groups are needed confirm the effects of statins on periprocedural cerebrovascular complications and restenosis after carotid stenting. © 2014 ege university press. all rights reserved.