The effect of povidone-iodine on peridural fibrosis in spinal surgery [Spinal cerrahi uygulamalarında povidon-iyotun peridural fibrozis üzerine etkisi: Deneysel çalışma]

Materials and methods: 24 albino rats were used for this experimental study. they were divided into three groups. in the first group (n=8) only th8-th12 laminectomy was performed (control group). in the second group (n=8),laminectomy area was irrigated with 2.5% concentrated povidone-iodine for 30s seconds. in the third group (n=8),laminectomy area was irrigated with 10% concentrated povidone-iodine for 30 seconds. in pathological specimens,fibrosis length and fibrosis area was calculated and compared between groups.results: peridural fibrosis length and fibrosis area didn't show statistically significant difference between all groups.conclusion: povidone-iodine has not increasing effect on peridural fibrosis so it may be safely used in spinal surgery when it is needed.aim: the purpose of this study was to evaluate whether povidone-iodine has any incremental effect on peridural fibrosis in spinal surgery. © 2014,ege university press. all rights reserved.