Effects of different duration time of exposure to 2100 MHz electromagnetic radiation on behaviour and hippocampal levels of protein kinases on rats [Sıçanlarda 2100 mhz elektromanyetik radyasyona farklı maruziyet sürelerinin davranış ve protein kinazların hipokampal seviyeleri üzerine etkileri]

Objectives: the aim of the present study was to investigate the effects of acute and chronic 2100 mhz radiofrequency-electromagnetic radiation (rf-emr) exposure on passive avoidance behaviour and hippocampal levels of protein kinases including camkiiα,pka,and p44/42 mapk from nmda dependent pathway in wistar rats. materials and methods: rats were divided into the following groups: sham-exposed rats and rats exposed to 2100 mhz rf-emr for 2 h/day for 1 and 10 weeks,respectively. passive avoidance task was used as a behavioural method. the hippocampal levels of selected kinases were measured using western blotting technique. results: findings demonstrated that both acute and chronic exposure to 2100 mhz rf-emr can impair the memory retention with less effect on chronic group of rats. in addition,hippocampal levels of selected protein kinases were higher in chronic groups than acute groups. conclusion: different duration times of 2100 mhz rf-emr exposure has different effects on both passive avoidance behaviour of rats and hippocampal levels of selected protein kinases. © 2018,ege university press. all rights reserved.