|
|
|
|
Intrajejunal infusion of 2-monoacylglycerol reduced food intake without inducing diarrhea in rats
|
|
|
|
|
|
|
|
نویسنده
|
okuma c. ,ohta t. ,ito m. ,tadaki h. ,oda t. ,kume s. ,nishiu j. ,kakutani m.
|
|
منبع
|
journal of pharmacological sciences - 2016 - دوره : 130 - شماره : 2 - صفحه:136 -138
|
|
چکیده
|
Some nutrients,such as carbohydrate,fat and protein,are known to stimulate satiety. however,the effect of sn-2-monoacylglycerol (2-mg),one of the digestive products of triglycerides,on food intake is still unclear. in the present study,the effects of 2-mg on food intake and diarrhea were evaluated and compared with long-chain fatty acid (lcfa) in rats by intrajejunal infusion. intrajejunal infusion of 2-mg reduced food intake. in addition,2-mg did not induce diarrhea at the condition that it comparably reduced food intake as compared with lcfa. these results suggest that 2-mg stimulates satiety without inducing diarrhea,different from lcfa. © 2016 japanese pharmacological society. production and hosting by elsevier b.v.
|
|
کلیدواژه
|
Diarrhea; Food intake; Monoacylglycerol
|
|
آدرس
|
biological/pharmacological research laboratories,central pharmaceutical research institute,japan tobacco inc.,1-1 murasaki-cho,takatsuki,osaka 569-1125, Japan, biological/pharmacological research laboratories,central pharmaceutical research institute,japan tobacco inc.,1-1 murasaki-cho,takatsuki,osaka 569-1125, Japan, biological/pharmacological research laboratories,central pharmaceutical research institute,japan tobacco inc.,1-1 murasaki-cho,takatsuki,osaka 569-1125, Japan, biological/pharmacological research laboratories,central pharmaceutical research institute,japan tobacco inc.,1-1 murasaki-cho,takatsuki,osaka 569-1125, Japan, biological/pharmacological research laboratories,central pharmaceutical research institute,japan tobacco inc.,1-1 murasaki-cho,takatsuki,osaka 569-1125, Japan, laboratory of animal physiology and functional anatomy,graduate school of agriculture,kyoto university,kitashirakawa oiwake-cho,sakyo-ku,kyoto 606-8502, Japan, biological/pharmacological research laboratories,central pharmaceutical research institute,japan tobacco inc.,1-1 murasaki-cho,takatsuki,osaka 569-1125, Japan, biological/pharmacological research laboratories,central pharmaceutical research institute,japan tobacco inc.,1-1 murasaki-cho,takatsuki,osaka 569-1125, Japan
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Authors
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|