High-flow nasal cannula and extubation success in the premature infant: a comparison of two modalities

Objective:to compare the effectiveness of fisher and paykel (fp) and vapotherm (vt) high-flow nasal cannula (hfnc) in preventing reintubation either within 72 h or <7 days after extubation of premature infants. the primary outcome was the rate of extubation failure defined as reintubation within 72 h. secondary outcomes included reintubation after ⩽7 days.study design:this was a prospective, randomized pilot study comparing the extubation success of 40 infants born between 26 and 29 weeks of gestation.result:the rate of extubation failure at 72 h was 18% for fp and 9% for vt. the failure rate ⩽7 days after extubation was 30% for fp and 27% for vt. none of these differences were statistically significant.conclusion:there was no difference between fp and vt in the extubation success of infants born between 26 and 29 weeks.