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Hyperammonemic coma in an ornithine transcarbamylase mutation carrier following antepartum corticosteroids
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نویسنده
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Lipskind S ,Loanzon S ,Simi E ,Ouyang D W
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منبع
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journal of perinatology - 2011 - دوره : 31 - شماره : 10 - صفحه:682 -684
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چکیده
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Women who are carriers of the ornithine transcarbamylase (otc) mutation are at risk for developing hyperammonemia during the postpartum period and at times of metabolic stress. we present a unique case of hyperammonemic coma occurring in an otc mutation carrier during the antepartum period. multiple factors, including the administration of antenatal corticosteroids, likely precipitated this critical condition. clinicians should be aware of this life-threatening clinical presentation and be prepared to identify, treat, and prevent hyperammonemia in affected individuals.
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آدرس
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Northwestern University Feinberg School of Medicine, Department of Obstetrics and Gynecology, USA, Saint Francis Hospital, Department of Obstetrics and Gynecology, USA, NorthShore University HealthSystem, University of Chicago Pritzker School of Medicine, Department of Obstetrics and Gynecology, USA, NorthShore University HealthSystem, University of Chicago Pritzker School of Medicine, Department of Obstetrics and Gynecology, USA
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Authors
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