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   Contribution of early glycemic status in the development of severe retinopathy of prematurity in a cohort of ELBW infants  
   
نویسنده Chavez-Valdez R ,McGowan J ,Cannon E ,Lehmann C U
منبع journal of perinatology - 2011 - دوره : 31 - شماره : 12 - صفحه:749 -756
چکیده    Objective:the objective of this study is to investigate the relationship between glycemic status and severe retinopathy of prematurity (rop).study design:this is a retrospective cohort study of 114 infants <1000 g admitted to a level iv neonatal intensive care unit within 48 h of life. a cumulative, time-weighted glucose level (twgl) derived from plotting glucose values over time was included in logistic regression analysis to identify predictors for severe rop.result:infants had 26.6±2 weeks gestational age and had a birth weight of 782±136 g. twgl during first 10 and 30 days of life were greater in the severe rop group (p<0.01). unlike single events of glucose levels ⩾150 mg dl−1, 10 days twgl ⩾100 mg dl−1 (odds ratio (or) 5.2, p<0.02) and 30 days twgl ⩾118 mg dl−1 (or 5.7, p<0.02) were predictors for severe rop (univariate). multivariate regression confirmed 30 days twgl ⩾118 mg dl−1 (or 9.4 to 10) and gram-positive sepsis (or 4.1 to 5) as predictors for severe rop (p<0.05).conclusion:high overall glycemic status is associated with the development of severe rop.
آدرس Texas Tech University Health Sciences Center, Division of Neonatology, Department of Pediatrics, USA. Johns Hopkins University School of Medicine, Division of Neonatology, Department of Pediatrics, USA, Johns Hopkins University School of Medicine, Division of Neonatology, Department of Pediatrics, USA. Drexel University College of Medicine, Division of Neonatology, Department of Pediatrics, USA, Texas Tech University Health Sciences Center, Division of Neonatology, Department of Pediatrics, USA, Johns Hopkins University School of Medicine, Division of Neonatology, Department of Pediatrics, USA
 
     
   
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