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Does increasing body mass index affect cerclage efficacy?
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نویسنده
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Poggi S H ,Vyas N A ,Pezzullo J C ,Landy H J ,Ghidini A
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منبع
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journal of perinatology - 2012 - دوره : 32 - شماره : 10 - صفحه:777 -779
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چکیده
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Objective:to study the relationship between body mass index (bmi) and gestational age (ga) at delivery in patients with cervical insufficiency (ci) undergoing cerclage.study design:we accessed a database of patients with singleton gestations undergoing cerclage (n=168) for a well-characterized history of ci, shortened cervix <2.5 cm with a history of prior preterm delivery or prolapse of membranes through the external os. univariate and multivariate logistic regression analysis were performed to compare obstetrical outcomes between obese and normal-weight patients.result:prior preterm delivery <35 weeks in obese vs normal-weight patients was significantly higher (44% vs 9%), odds ratio=6.9 (95% ci: 2.5, 18.5), with lower mean ga at delivery (32.6±7.0 vs 37.2±3.4 weeks, p<0.001). after controlling for confounders, bmi remained significantly predictive of prematurity (coefficient: −0.12, adjusted r2=0.24), such that every additional 1 unit of bmi was associated with a 1-day reduction in ga at delivery (p=0.03).conclusion:an inverse correlation exists between bmi and ga at delivery in patients with ci receiving cerclage. the findings are unexpected given the protective effect of obesity on spontaneous preterm delivery.
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آدرس
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Inova Alexandria Hospital, USA. Georgetown University Hospital, Department of Obstetrics and Gynecology, USA, Georgetown University Hospital, Department of Obstetrics and Gynecology, USA, Georgetown University Hospital, Department of Biomathematics and Biostatistics, USA, Georgetown University Hospital, Department of Obstetrics and Gynecology, USA, Inova Alexandria Hospital, USA. Georgetown University Hospital, Department of Obstetrics and Gynecology, USA
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Authors
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