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U-500R and aspart insulin for the treatment of severe insulin resistance in pregnancy associated with pregestational diabetes
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نویسنده
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Okeigwe I ,Yeaton-Massey A ,Kim S ,Vargas J E ,Murphy E J
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منبع
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journal of perinatology - 2013 - دوره : 33 - شماره : 3 - صفحه:235 -238
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چکیده
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Severe insulin resistance as a complication of diabetes in pregnancy is seen with increasing frequency. treatment with large doses of insulin (>300 units perday) can be practically difficult. a woman with preexisting type 2 diabetes mellitus and poor glycemic control presented in early pregnancy requiring over 1000 units of insulin daily. she was transitioned to subcutaneous u-500 (concentrated regular insulin) in combination with a rapid-acting insulin analog achieving good glycemic control and good maternal and fetal outcomes. u-500r insulin in conjunction with a rapid-acting insulin analog can be used safely in early pregnancy to improve glycemic control in severe insulin resistance due to pregestational diabetes.
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آدرس
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University of California at San Francisco and San Francisco General Hospital, Department of Obstetrics, USA. Boston University Medical Center Department of Obstetrics and Gynecology, USA, University of California at San Francisco and San Francisco General Hospital, Department of Obstetrics, USA. Stanford University Department of Obstetrics and Gynecology, USA, University of California at San Francisco General Hospital, Division of Endocrinology and Metabolism, USA, University of California at San Francisco and San Francisco General Hospital, Department of Obstetrics, USA, University of California at San Francisco General Hospital, Division of Endocrinology and Metabolism, USA
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Authors
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