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Evaluating retinopathy of prematurity screening guidelines for 24- to 27-week gestational age infants
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نویسنده
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Kennedy K A ,Wrage L A ,Higgins R D ,Finer N N ,Carlo W A ,Walsh M C ,Laptook A R ,Faix R G ,Yoder B A ,Schibler K ,Gantz M G ,Das A ,Newman N S ,Phelps D L
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منبع
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journal of perinatology - 2014 - دوره : 34 - شماره : 4 - صفحه:311 -318
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چکیده
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Objective:to determine whether current retinopathy of prematurity (rop) screening guidelines adequately identify treatable rop in a contemporary cohort of extremely low gestation infants.study design:data from the surfactant, positive pressure, and pulse oximetry randomized trial were used. inborn infants of 24 0/7 to 27 6/7 weeks gestational age (ga) with consent before delivery were enrolled in 2005 to 2009. severe rop (type 1 rop or treatment with laser, cryotherapy or bevacizumab) or death was the primary outcome for the randomized trial. examinations followed the then current aap (american academy of pediatrics) screening recommendations, beginning by 31 to 33 weeks postmenstrual age (pma).result:one thousand three hundred and sixteen infants were enrolled in the trial. nine hundred and ninety-seven of the 1121 who survived to first eye exam had final rop outcome determined. one hundred and thirty-seven (14% of 997) met criteria for severe rop and 128 (93%) of those had sufficient data (without missing or delayed exams) to determine age of onset of severe rop. pma at onset was 32.1 to 53.1 weeks. in this referral center cohort, 1.4% (14/997) developed severe rop after discharge.conclusion:our contemporary data support the 2013 aap screening guidelines for rop for infants of 24 0/7 to 27 6/7 weeks ga. some infants do not meet treatment criteria until after discharge home. post-discharge follow-up of infants who are still at risk for severe rop is crucial for timely detection and treatment.
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آدرس
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University of Texas Medical School at Houston, Department of Pediatrics, USA, Biostatistics and Epidemiology Division, RTI International, USA, National Institutes of Health, USA, University of California at San Diego, Department of Pediatrics, USA, University of Alabama at Birmingham, Division of Neonatology, USA, Case Western Reserve University, Department of Pediatrics, USA, Brown University, Department of Pediatrics, USA, University of Utah School of Medicine, Department of Pediatrics, Division of Neonatology, USA, University of Utah School of Medicine, Department of Pediatrics, Division of Neonatology, USA, Cincinnati Children’s Hospital Medical Center and University of Cincinnati, Department of Pediatrics, USA, Biostatistics and Epidemiology Division, RTI International, USA, Biostatistics and Epidemiology Division, RTI International, USA, Case Western Reserve University, Department of Pediatrics, USA, University of Rochester Medical Center, Department of Pediatrics, USA
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Authors
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