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The impact of neurally adjusted ventilatory assist mode on respiratory severity score and energy expenditure in infants: a randomized crossover trial
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نویسنده
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Rosterman J L ,Pallotto E K ,Truog W E ,Escobar H ,Meinert K A ,Holmes A ,Dai H ,Manimtim W M
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منبع
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journal of perinatology - 2018 - دوره : 38 - شماره : 1 - صفحه:59 -63
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چکیده
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Objective:examine respiratory severity scores (rss) (mean airway pressure × fraction of inspired oxygen) and resting energy expenditure (ree) on neurally adjusted ventilatory assist (nava) compared with synchronized intermittent mandatory ventilation with pressure controlled and supported breath (simv (pc)ps).study design:a randomized, crossover trial in a level iv neonatal intensive care unit. twenty-four patients were ventilated with nava or simv (pc) ps for 12 h and then crossed over to the alternative mode for 12 h. the primary outcome (rss) and additional secondary respiratory outcomes were analyzed.results:rss and measured ree were not different between modes. on nava, peak inspiratory pressures were lower (17.8 vs 19.9 cmh2o (p<0.05)) without higher oxygen requirements. respiratory rates were higher on nava (52 vs 39 (p<0.05)), estimated work of breathing (wob) (0.01 vs 0.04 j l−1 (p<0.05)) was improved.conclusion:nava mode can be safe without increase in rss or ree. although respiratory rates were higher, this was offset by lower peak inspiratory pressures and wob during nava.
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آدرس
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University of Missouri-Kansas City School of Medicine, USA, University of Missouri-Kansas City School of Medicine, USA, University of Missouri-Kansas City School of Medicine, USA, University of Missouri-Kansas City School of Medicine, USA, University of Missouri-Kansas City School of Medicine, USA, University of Missouri-Kansas City School of Medicine, USA, University of Missouri-Kansas City School of Medicine, USA, University of Missouri-Kansas City School of Medicine, USA
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Authors
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