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Racial differences in neonatal hypoglycemia among very early preterm births
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نویسنده
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James-Todd Tamarra ,March Melissa I. ,Seiglie Jacqueline ,Gupta Munish ,Brown Florence M. ,Majzoub Joseph A.
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منبع
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journal of perinatology - 2018 - دوره : 38 - شماره : 3 - صفحه:258 -263
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چکیده
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Objective:to determine whether the prevalence of neonatal hypoglycemia differs by race/ethnicity.study design:a retrospective cohort study using prospectively collected data from 515 neonates born very preterm (<32 weeks) to normoglycemic women and admitted to the neonatal intensive care unit (nicu) at a major tertiary hospital in boston, ma, between 2008 and 2012.results:a total of 61%, 12%, 7%, 7%, and 13% were white, black, hispanic, asian, and other, respectively. among the 66% spontaneous preterm births, 63% of the black neonates experienced hypoglycemia (blood glucose level < 40 mg/dl), while only 22–30% of the other racial/ethnic neonates did so (black vs. white rr 2.15; 95% ci: 1.54–3.00). after adjusting for maternal education, maternal age, multiple gestations, delivery type, gestational age, birth weight, and neonates’ sex, this association remained significant (adjusted black vs. white rr: 1.61, 95% ci: 1.13–2.29). an increased risk of infant hypoglycemia was not seen in infants of other racial/ethnic groups, nor in any racial/ethnic group with a medically indicated preterm birth.conclusions:black neonates delivered for spontaneous (but not medical) indications at <32 weeks had a higher risk of hypoglycemia, which could provide critical information about mechanisms of preterm birth and adverse postnatal outcomes in this high-risk group.
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آدرس
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Harvard T.H. Chan School of Public Health, Departments of Environmental Health and Epidemiology, USA. Brigham and Women’s Hospital, Division of Women’s Health, Department of Medicine, USA, Beth Israel Deaconess Medical Center, Department of Obstetrics and Gynecology, USA. University Hospitals, Department of Obstetrics and Gynecology, USA, Massachusetts General Hospital, Department of Medicine, USA, Beth Israel Deaconess Medical Center, Department of Neonatology, USA, Joslin Diabetes Center, Division of Adult Diabetes, USA, Boston Children’s Hospital, Division of Endocrinology, USA
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Authors
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