Do preterm infants with a birth weight ≤1250 g born to single-parent families have poorer neurodevelopmental outcomes at age 3 than those born to two-parent families?

Objectiveinvestigate neurodevelopmental outcomes at 3 years corrected age in infants with a birth weight ≤1250 g born to single parents.study designinfants born between 1995 and 2010 with a birth weight ≤1250 g were considered eligible. primary outcome was neurodevelopmental impairment; considered present if a child had any of the following: cerebral palsy, cognitive delay, visual impairment, or deafness/neurosensory hearing impairment. univariate and multivariate analyses were performed.resulta total of 1900 infants were eligible for inclusion. follow-up data were available for 1395; 88 were born to a single parent. infants in the single-parent group had higher mortality (18% vs. 11%, p = 0.009), iq ≥1 sd below the mean (40% vs. 21%, p = 0.001) and any neurodevelopmental impairment (47% vs. 29%, p = 0.003). single-parent family status, maternal education, bronchopulmonary dysplasia and severe neurological injury were significant predictors of intellectual impairment at 3 years corrected age.conclusionpreterm infants with a birth weight ≤1250 g born to single parents at birth have poorer intellectual functioning at 3 years corrected age.