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Effect of a lifestyle intervention during pregnancy—findings from the Finnish gestational diabetes prevention trial (RADIEL)
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نویسنده
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Rönö Kristiina ,Grotenfelt Nora Elisabeth ,Klemetti Miira Marjuska ,Stach-Lempinen Beata ,Huvinen Emilia ,Meinilä Jelena ,Valkama Anita ,Tiitinen Aila ,Roine Risto Paavo ,Pöyhönen-Alho Maritta ,Andersson Sture ,Laivuori Hannele ,Kautiainen Hannu ,Eriksson Johan Gunnar ,Koivusalo Saila Birgitta
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منبع
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journal of perinatology - 2018 - دوره : 38 - شماره : 9 - صفحه:1157 -1164
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چکیده
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Objectiveto assess the effect of lifestyle counseling on perinatal outcomes among women at high risk for gestational diabetes.study designa total of 492 women with obesity and/or prior gestational diabetes were allocated to intervention (four sessions of lifestyle counseling, n = 249) or usual care (n = 243) before 20 weeks’ gestation.resultlifestyle indicators, gestational weight gain, or obstetric and perinatal outcomes did not differ between the two groups. an oral glucose tolerance test in the first half of pregnancy was pathological in 37.7% (n = 87/144) of intervention and 36.5% (n = 72/197) of control group women (p = 0.81). the total incidence of gestational diabetes diagnosed in the first or second half of pregnancy was 44.8% (107/239) in the intervention and 48.1% (111/231) in the control group (p = 0.48).conclusionsthe high prevalence of impaired glucose metabolism was observed already in early pregnancy, which may have contributed to the lack of effect of the intervention.
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آدرس
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University of Helsinki and Helsinki University Hospital, Finland, University of Helsinki and Helsinki University Hospital, Unit of General Practice and Primary Health Care, Finland, University of Helsinki and Helsinki University Hospital, Finland. South Karelia Central Hospital, Finland, South Karelia Central Hospital, Finland, University of Helsinki and Helsinki University Hospital, Finland, University of Helsinki and Helsinki University Hospital, Unit of General Practice and Primary Health Care, Finland, University of Helsinki and Helsinki University Hospital, Unit of General Practice and Primary Health Care, Finland. Folkhälsan Research Center, Finland, University of Helsinki and Helsinki University Hospital, Finland, University of Eastern Finland, Department of Health and Social Management, Finland. Kuopio University Hospital, Finland. University of Helsinki and Helsinki University Hospital, Finland, University of Helsinki and Helsinki University Hospital, Finland, University of Helsinki and Helsinki University Hospital, Finland, University of Helsinki and Helsinki University Hospital, Finland. Helsinki Institute of Life Science, Finland. University of Tampere, Finland. Tampere University Hospital, Department of Obstetrics and Gynecology, Finland, University of Helsinki and Helsinki University Hospital, Unit of General Practice and Primary Health Care, Finland. University of Eastern Finland, Finland, University of Helsinki and Helsinki University Hospital, Unit of General Practice and Primary Health Care, Finland. Folkhälsan Research Center, Finland. National Institute for Health and Welfare, Department of Chronic Disease Prevention, Finland, University of Helsinki and Helsinki University Hospital, Finland
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Authors
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