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Understanding health disparities
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نویسنده
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Stevenson David K. ,Wong Ronald J. ,Aghaeepour Nima ,Angst Martin S. ,Darmstadt Gary L. ,DiGiulio Daniel B. ,Druzin Maurice L. ,Gaudilliere Brice ,Gibbs Ronald S. ,Gould Jeffrey B. ,Katz Michael ,Li Jingjing ,Moufarrej Mira N. ,Quaintance Cecele C. ,Quake Stephen R. ,Relman David A. ,Shaw Gary M. ,Snyder Michael P. ,Wang Xiaobin ,Wise Paul H.
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منبع
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journal of perinatology - 2019 - دوره : 39 - شماره : 3 - صفحه:354 -358
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چکیده
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Based upon our recent insights into the determinants of preterm birth, which is the leading cause of death in children under five years of age worldwide, we describe potential analytic frameworks that provides both a common understanding and, ultimately the basis for effective, ameliorative action. our research on preterm birth serves as an example that the framing of any human health condition is a result of complex interactions between the genome and the exposome. new discoveries of the basic biology of pregnancy, such as the complex immunological and signaling processes that dictate the health and length of gestation, have revealed a complexity in the interactions (current and ancestral) between genetic and environmental forces. understanding of these relationships may help reduce disparities in preterm birth and guide productive research endeavors and ultimately, effective clinical and public health interventions.
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آدرس
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Stanford University School of Medicine, Department of Pediatrics, USA, Stanford University School of Medicine, Department of Pediatrics, USA, Stanford University School of Medicine, Department of Anesthesiology, USA, Stanford University School of Medicine, Department of Anesthesiology, USA, Stanford University School of Medicine, Department of Pediatrics, USA, Stanford University School of Medicine, Department of Medicine, USA. Infectious Diseases Section, Veterans Affairs Palo Alto Health Care System, USA, Stanford University School of Medicine, Department of Obstetrics and Gynecology, USA, Stanford University School of Medicine, Department of Anesthesiology, USA, Stanford University School of Medicine, Department of Obstetrics and Gynecology, USA, Stanford University School of Medicine, Department of Pediatrics, USA, Stanford University School of Medicine, Department of Pediatrics, USA, Stanford University School of Medicine, Department of Pediatrics, Department of Genetics, USA, Stanford University and Chan Zuckerberg Biohub, Departments of Bioengineering and Applied Physics, USA, Stanford University School of Medicine, Department of Pediatrics, USA, Stanford University and Chan Zuckerberg Biohub, Departments of Bioengineering and Applied Physics, USA, Stanford University School of Medicine, Department of Medicine, USA. Infectious Diseases Section, Veterans Affairs Palo Alto Health Care System, USA, Stanford University School of Medicine, Department of Pediatrics, USA, Stanford University School of Medicine, Department of Genetics, USA, Johns Hopkins University, Department of Population, USA. Johns Hopkins University School of Medicine, Department of Pediatrics, USA, Stanford University School of Medicine, Department of Pediatrics, USA
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Authors
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