|
|
|
|
Prenatally diagnosed omphalocele: characteristics associated with adverse neonatal outcomes
|
|
|
|
|
|
|
|
نویسنده
|
Chock Valerie Y. ,Davis Alexis S. ,Cho Seo-Ho ,Bax Christina ,Fluharty Elizabeth ,Weigel Nicole ,Homeyer Margaret ,Hudgins Louanne ,Jones Richard ,Rubesova Erika ,Sylvester Karl G. ,Blumenfeld Yair J. ,Hintz Susan R.
|
|
منبع
|
journal of perinatology - 2019 - دوره : 39 - شماره : 8 - صفحه:1111 -1117
|
|
چکیده
|
Objectiveto characterize factors associated with adverse neonatal outcomes in prenatally diagnosed omphalocele cases.study designprenatally diagnosed omphalocele cases at a single referral center from 1 january 2009 to 31 december 2017 were retrospectively reviewed. clinical variables and antenatal imaging measurements were collected. associations between prenatal and neonatal characteristics and the adverse outcome of death or prolonged length of stay (los) were analyzed.resultsout of 63 fetal cases, 33 were live-born, > 50% had other anomalies, and neonatal mortality was 12%. adverse outcomes were associated with neonatal variables, including lower median 1-min apgar score, initial mechanical ventilation, and late-onset sepsis, but not approach to omphalocele closure. with multivariate analysis, death or prolonged los was associated only with low lung volumes by fetal mri (or 34 (3–422), p = 0.006).conclusionlow lung volumes by fetal mri were associated with death or prolonged los in neonates with prenatally diagnosed omphalocele and may guide clinicians with counseling families.
|
|
|
|
|
آدرس
|
Stanford University School of Medicine, Division of Neonatal and Developmental Medicine, Department of Pediatrics, USA. Lucile Packard Children’s Hospital Stanford, Fetal and Pregnancy Health Program, USA, Stanford University School of Medicine, Division of Neonatal and Developmental Medicine, Department of Pediatrics, USA. Lucile Packard Children’s Hospital Stanford, Fetal and Pregnancy Health Program, USA, Stanford University School of Medicine, Division of Neonatal and Developmental Medicine, Department of Pediatrics, USA. Stanford Prevention Research Center, USA, University of Pennsylvania, USA, Stanford University School of Medicine, Division of Neonatal and Developmental Medicine, Department of Pediatrics, USA. Lucile Packard Children’s Hospital Stanford, Fetal and Pregnancy Health Program, USA, Stanford University School of Medicine, Division of Neonatal and Developmental Medicine, Department of Pediatrics, USA. Lucile Packard Children’s Hospital Stanford, Fetal and Pregnancy Health Program, USA, Lucile Packard Children’s Hospital Stanford, Fetal and Pregnancy Health Program, USA. Stanford University School of Medicine, Division of Medical Genetics, Department of Pediatrics, USA, Lucile Packard Children’s Hospital Stanford, Fetal and Pregnancy Health Program, USA. Stanford University School of Medicine, Division of Medical Genetics, Department of Pediatrics, USA, Stanford University School of Medicine, Department of Radiology, USA, Lucile Packard Children’s Hospital Stanford, Fetal and Pregnancy Health Program, USA. Stanford University School of Medicine, Department of Radiology, USA, Lucile Packard Children’s Hospital Stanford, Fetal and Pregnancy Health Program, USA. Stanford University School of Medicine, Department of Pediatric Surgery, USA, Lucile Packard Children’s Hospital Stanford, Fetal and Pregnancy Health Program, USA. Stanford University School of Medicine, Department of Obstetrics and Gynecology, USA, Stanford University School of Medicine, Division of Neonatal and Developmental Medicine, Department of Pediatrics, USA. Lucile Packard Children’s Hospital Stanford, Fetal and Pregnancy Health Program, USA
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Authors
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|