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Risk of development of treated retinopathy of prematurity in very low birth weight infants
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نویسنده
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Gonski Samantha ,Hupp Susan R. ,Cotten C. Michael ,Clark Reese H. ,Laughon Matthew ,Watt Kevin ,Hornik Christoph P. ,Kumar Karan ,Smith P. Brian ,Greenberg Rachel G.
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منبع
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journal of perinatology - 2019 - دوره : 39 - شماره : 11 - صفحه:1562 -1568
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چکیده
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Objectivequantify the risk of treatment for retinopathy of prematurity (rop) among infants meeting current u.s. screening guidelines.study designamong infants ≤1500 g birth weight or ≤30 weeks gestation screened for rop from 2006–2015, we developed a risk prediction model to identify infants treated for rop. we applied our model to a separate infant cohort discharged in 2016.resultseventy-five thousand eight hundred and twenty one infants met inclusion criteria; 2306 (3%) were treated for rop. infants with several risk factor combinations (no ventilator support or oxygen on postnatal day 28, no history of necrotizing enterocolitis, and no intraventricular hemorrhage) were at low risk of rop. applied to 6127 infants discharged in 2016, our model had 97.9% sensitivity, 63.3% specificity, positive predictive value of 4.0%, and negative predictive value of 99.9%.conclusionlarge numbers of infants at low risk of developing rop are required to undergo screening. refining current rop guidelines may reduce unnecessary examinations.
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آدرس
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North Carolina School of Science and Mathematics, USA, University of Texas Southwestern Medical Center, Department of Pediatrics, USA, Duke University, Department of Pediatrics, USA, Pediatrix-Obstetrix Center for Research and Education, USA, University of North Carolina at Chapel Hill, Division of Neonatal-Perinatal Medicine, USA, Duke University, Department of Pediatrics, USA. Duke Clinical Research Institute, USA, Duke University, Department of Pediatrics, USA. Duke Clinical Research Institute, USA, Duke University, Department of Pediatrics, USA, Duke University, Department of Pediatrics, USA. Duke Clinical Research Institute, USA, Duke University, Department of Pediatrics, USA. Duke Clinical Research Institute, USA
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Authors
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