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Effect of gestational subclinical hypothyroidism on early neurodevelopment of offspring
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نویسنده
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Chen L-M ,Chen Q-S ,Jin G-X ,Si G-X ,Zhang Q ,Ye E-l ,Yang H ,Cai L-Q ,Peng M-M ,Lin Z-Z ,Yu L-C ,Zhang C ,Lu X-M
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منبع
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journal of perinatology - 2015 - دوره : 35 - شماره : 9 - صفحه:678 -682
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چکیده
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Objective:to evaluate the effects of gestational subclinical hypothyroidism (sch) on early neurodevelopment of offspring.study design:a prospective study included 106 infants born to mothers with gestational sch and 106 infants born to mothers who were euthyroid during pregnancy. the neurodevelopment of 12 to 24-month-old infants was assessed and compared using the gesell developmental test (revised version).results:infants born to mothers with gestational sch and those born to euthyroid mothers had similar scores on the gesell development test. no correlations were observed between maternal tsh concentration and gesell developmental test scores of offspring. infants born to mothers who had gestational sch during the first trimester specifically and those born to euthyroid mothers had similar scores on the gesell development test. no significant correlations were detected between maternal tsh concentration during the first trimester and offspring neurodevelopment.conclusions:no detectable neurodevelopment deficit was observed in offspring up to 24 months old from mothers who had gestational sch.
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آدرس
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Third Affiliated Hospital of Wenzhou Medical University, Department of Endocrinology, China. Wenzhou Medical University, China, Wenzhou People’s Hospital, Department of Endocrinology, China, Third Affiliated Hospital of Wenzhou Medical University, Department of Pediatrics, China, Jining First People’s Hospital, Department of Endocrinology, China, Taizhou First People’s Hospital, China, Third Affiliated Hospital of Wenzhou Medical University, Department of Endocrinology, China. Wenzhou Medical University, China, Third Affiliated Hospital of Wenzhou Medical University, Department of Endocrinology, China. Wenzhou Medical University, China, Third Affiliated Hospital of Wenzhou Medical University, Department of Endocrinology, China. Wenzhou Medical University, China, Third Affiliated Hospital of Wenzhou Medical University, Department of Endocrinology, China. Wenzhou Medical University, China, Third Affiliated Hospital of Wenzhou Medical University, Department of Endocrinology, China. Wenzhou Medical University, China, Third Affiliated Hospital of Wenzhou Medical University, Department of Endocrinology, China. Wenzhou Medical University, China, Third Affiliated Hospital of Wenzhou Medical University, China. Wenzhou Medical University, China, Third Affiliated Hospital of Wenzhou Medical University, Department of Endocrinology, China. Wenzhou Medical University, China
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Authors
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