Comparison of three types of intervention to enhance placental redistribution in term newborns: randomized control trial

Objective:to compare the effect of combined delayed cord clamping and umbilical cord milking to either of them had done alone, on hematological parameters at 6 weeks of age in term neonates.study design:it was a randomized controlled trial, conducted during january to december 2014. three hundred eligible neonates were randomly allocated to three parallel groups. primary outcome was hemoglobin and serum ferritin at 6 weeks of age. data were analyzed using analysis of variance and kruskal–wallis test.results:baseline characteristics and hemodynamic parameters were comparable in all the three groups. the median serum ferritin level at 6 weeks was significantly higher in the group receiving both delayed cord clamping and milking the cut cord group (295.49 (233.5 to 346.54) ng ml−1) as compared with the group that received only milking of the cut cord (184.55 (131.22 to 256.5) ng ml−1) or only delayed cord clamping (268.8 (189.4 to 315.44) ng ml−1).conclusion:delayed cord clamping with milking the cut cord improved iron stores at 6 weeks of age in term infants, then either of the two interventions alone.