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A decision-making tool for exchange transfusions in infants with severe hyperbilirubinemia in resource-limited settings
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نویسنده
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Olusanya B O ,Iskander I F ,Slusher T M ,Wennberg R P
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منبع
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journal of perinatology - 2016 - دوره : 36 - شماره : 5 - صفحه:338 -341
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چکیده
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Late presentation and ineffective phototherapy account for excessive rates of avoidable exchange transfusions (ets) in many low- and middle-income countries. several system-based constraints sometimes limit the ability to provide timely ets for all infants at risk of kernicterus, thus necessitating a treatment triage to optimize available resources. this article proposes a practical priority-setting model for term and near-term infants requiring et after the first 48 h of life. the proposed model combines plasma/serum bilirubin estimation, clinical signs of acute bilirubin encephalopathy and neurotoxicity risk factors for predicting the risk of kernicterus based on available evidence in the literature.
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آدرس
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Centre for Healthy Start Initiative, Nigeria, Cairo University, Department of Pediatrics, Egypt, University of Minnesota, Department of Pediatrics, USA, University of Washington, Department of Pediatrics, USA
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Authors
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